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A drug, mosunetuzumab, to treat follicular lymphoma that has not yet been treated

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18 and older

Phase 2

9 Locations

NCT05389293

Clinical Trial Goal


To find out if mosunetuzumab is safe and works well to treat follicular lymphoma that has not yet been treated

You may be able to join this trial if you:


  • Are 18 years old or older
  • Have newly diagnosed follicular lymphoma that needs treatment 
  • Have not received any treatment for the lymphoma
  • Do not have lymphoma in your brain or spinal cord
  • Have not had a blood or marrow transplant (BMT)
  • Agree to have other standard tests done to see if you can be in the clinical trial 

Trial Details


Mosunetuzumab is a T-cell engaging bispecific antibody that target CD20 and CD3 on certain cells.
 
You’ll get: 
  • Mosunetuzumab – Given as a shot under your skin 1 time each week for 4 weeks, then 1 time every 3 weeks

You may continue treatment for about 6-12 months depending on how well it's working. You'll have biopsies and/or scans to see how well the treatment is working. The clinical trial doctors will check your health for up to 1 year.

The Food and Drug Administration (FDA) has approved mosunetuzumab to treat follicular lymphoma that has that has come back (relapsed) or has not gotten better with treatment (refractory).

Contacts


Lorenzo Falchi, MD, 646-608-3705, FalchiL@mskcc.org

Gilles Salles, MD, PhD, 646-608-4153, SallesG@mskcc.org

Locations

Georgetown University (Data Collection Only)RECRUITING

Washington D.C., District of Columbia
Joseph Roswarski, MD, 202-444-2223

Hackensack Meridian Health (Data collection only)RECRUITING

Hackensack, New Jersey
Lori Leslie, MD, 551-996-3033

Memorial Sloan Kettering at Basking Ridge Limited Protocol ActivitiesRECRUITING

Basking Ridge, New Jersey
Lorenzo Falchi, MD, 646-608-3705

Memorial Sloan Kettering Bergen (Limited Protocol Activities)RECRUITING

Montvale, New Jersey
Lorenzo Falchi, MD, 646-608-3705

Memorial Sloan Kettering Monmouth (Limited protocol activities)RECRUITING

Middletown, New Jersey
Lorenzo Falchi, MD, 646-608-3705

Memorial Sloan Kettering Cancer CenterRECRUITING

New York, New York
Lorenzo Falchi, MD, 646-608-3705, FalchiL@mskcc.org

Memorial Sloan Kettering Nassau (Limited protocol activities)RECRUITING

Rockville Centre, New York
Lorenzo Falchi, MD, 646-608-3705

Memorial Sloan Kettering Suffolk- Commack (Limited protocol activities)RECRUITING

Commack, New York
Lorenzo Falchi, MD, 646-608-3705

Memorial Sloan Kettering Westchester (Limited protocol activities)RECRUITING

Harrison, New York
Lorenzo Falchi, MD, 646-608-3705

ClinicalTrials.gov record


NCT05389293. First posted on 5/25/22

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