Clinical Trial Goal
To find out:
- The highest dose of TLN-121 that's safe to give
- If TLN-121, alone and in combination with TLN-254, is safe and works well to treat NHL that has relapsed or is refractory
You may be able to join this trial if you:
- Are 18 years old or older
- Have NHL that has relapsed or is refractory. Some examples include:
- Diffuse large B-cell lymphoma (DLBCL)
- Follicular lymphoma
- Peripheral T-cell lymphoma (PTCL)
- Do not have lymphoma in your brain or spinal cord
- Have not had an allogeneic (cells from a donor) blood or marrow transplant (BMT) in the last 3 months
- Have not had an autologous (your own cells) BMT in the last 2 months
- Agree to have other standard tests done to see if you can be in the clinical trial
Trial Details
TLN-121 is a drug that doctors believe will find and attack cancer cells.
TLN-254 is a drug that doctors believe will find and attack cancer cells.
You’ll get:
TLN-254 is a drug that doctors believe will find and attack cancer cells.
You’ll get:
- TLN-121 – The dose you'll get depends on when you start the trial and how safe it has been
- TLN-254 – The dose you'll get depends on when you start the trial and how safe it has been
You'll have scans to see how well the treatment is working. The clinical trial doctors will check your health for up to 2 years.
The Food and Drug Administration (FDA) has not yet approved TLN-121 or TLN-254.
Locations
The START Center for Cancer Care - MidwestRECRUITING
Grand Rapids, Michigan
Andrew Sochacki, 616-389-1800, andrew.sochacki@startmidwest.com
Washington University School of MedicineRECRUITING
St Louis, Missouri
Amalia Dubois, 314-273-1486, amalia@wustl.edu
SCRI Oncology PartnersRECRUITING
Nashville, Tennessee
Principal Investigator, (615) 339-0516, Sydney.Fitzgerald@scri.com
The University of Texas MD Anderson Cancer CenterRECRUITING
Houston, Texas
Dai Chihara, Dr., 713-792-2860, DChihara@mdanderson.org
Sponsors
lead: Treeline Biosciences, Inc.
