Clinical Trial Goal
To find out if alendronate is safe and works well to treat osteonecrosis in adults with SCD
You may be able to join this trial if you:
- Are 18-80 years old
- Have SCD and osteonecrosis
- Agree to have other standard tests done to see if you can be in the clinical trial
Trial Details
Alendronate is a drug that is used to treat and prevent osteoporosis.
You’ll get:
You’ll get:
- Alendronate – A pill that you take by mouth 1 time each week
You may continue treatment for up to 6 months. The clinical trial doctors will check your health for up to 7 months.
The Food and Drug Administration (FDA) has alendronate to treat and prevent osteoporosis. Using it in this way to treat osteonecrosis in adults with SCD is new and unproven.
Locations
UC Davis Comprehensive Cancer CenterRECRUITING
Sacramento, California
Contacts:
- Leyla Y Teos, PhD, 916-460-2749, lyteos@ucdavis.edu
- Oyebimpe O Adesina, MD, MS, (916) 703-5166, adesina@ucdavis.edu
Sponsors
collaborator: National Heart, Lung, and Blood Institute (NHLBI), collaborator: Doris Duke Charitable Foundation, lead: University of California, Davis

