Clinical Trial Goal
To find out if a combination of chemo and radiation therapy is safe and works well to treat nasal NK cell lymphoma that has not yet been treated
You may be able to join this trial if you:
- Are 18 years old or older
- Have stage 1 or 2 nasal NK cell lymphoma that has not yet been treated
- Agree to have other standard tests done to see if you can be in the clinical trial
Trial Details
You’ll get radiation therapy – Given 5 days each week for up to 6 weeks.
You’ll also get treatment with the following chemo drugs in cycles that last 3 weeks. You could get treatment for up to 9 weeks:
You’ll also get treatment with the following chemo drugs in cycles that last 3 weeks. You could get treatment for up to 9 weeks:
- Dexamethasone – Given as an intravenous (IV) infusion 1 time each day for 3 days each cycle
- Etoposide – Given as an IV infusion 1 time each day for 3 days each cycle
- Ifosfamide – Given as an IV infusion 1 time each day for 3 days each cycle
- Mesna – Given as a continuous IV infusion for 3 days each cycle
- Carboplatin – Given as an IV infusion 1 time on the 1st day of each cycle
The clinical trial doctors will check your health for about 5 years. You'll have an electrocardiogram (test of your heart’s activity, measured through wires taped to your chest) and scans to see how well the treatment is working.
The Food and Drug Administration (FDA) has approved all the drugs used in this trial, but using them with radiation therapy to treat nasal NK cell lymphoma is new and unproven.
Locations
MD Anderson Cancer CenterRECRUITING
Houston, Texas
Bouthaina Dabaja, MD, 713-563-2300, bdabaja@mdanderson.org
Sponsors
lead: M.D. Anderson Cancer Center
