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A drug, teclistamab, to treat multiple myeloma that has come back (relapsed) or not gotten better with treatment (refractory)

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18 - 99

Phase 2

13 Locations

NCT06171685

Clinical Trial Goal


To find out:
  • The highest dose of teclistamab that's safe to give
  • If teclistamab is safe and works well to treat multiple myeloma that has relapsed or is refractory

You may be able to join this trial if you:


  • Are 18 years old or older
  • Have multiple myeloma that has relapsed or is refractory
  • Do not have any of the following:
    • Amyloidosis
    • Plasma cell leukemia
    • POEMS Syndrome
    • Waldensrom's macroglobulinemia
  • Agree to have other standard tests done to see if you can be in the clinical trial 

Trial Details


Teclistamab is a bispecific antibody that targets BCMA and CD3 on certain cells. 

You’ll get:
  • Teclistamab – Given as intravenous (IV) infusions. The dose you'll get depends on when you start the trial and how safe it has been

You'll have biopsies and/or scans to see how well the treatment is working. 

The Food and Drug Administration (FDA) has approved all of the drugs used in this trial. 

Contacts


Jessica Vandermark, (203) 354-7215, vandermarkj@themmrf.org

Mercedes Martillo, martillom@themmrf.org

Locations

City of HopeRECRUITING

Duarte, California
Ann Morales, 8666760760, amamanee@coh.org

Emory Winship Cancer CenterRECRUITING

Atlanta, Georgia
Bryan Burton, 1-888-946-7447, bryan.james.burton@emory.edu

University of Chicago Cancer CenterRECRUITING

Chicago, Illinois
Anna Pula, 1-855-702-8222, anna.pula@bsd.uchicago.edu

Beth Israel Deaconess Medical CenterRECRUITING

Boston, Massachusetts
Rong Wang, 617-667-7000, rwang8@bidmc.harvard.edu

Dana Farber Cancer Institute/Harvard Medical SchoolRECRUITING

Boston, Massachusetts
Sean Rowell, 877-442-3324, seanm_rowell@dfci.harvard.edu

Barbara Ann Karmanos Cancer CenterRECRUITING

Detroit, Michigan
Christiane Houde, (800) 527-6266, houdec@karmanos.org

Mayo Clinic RochesterNOT_YET_RECRUITING

Rochester, Minnesota
Jessica Haug, 844-544-0036, haug.jessica@mayo.edu

Washington University MedicineRECRUITING

St Louis, Missouri
Blake Pickard, 314-362-5000, blakep@wustl.edu

Hackensack University Medical CenterRECRUITING

Hackensack, New Jersey
Fideliza Perez, 844-464-9355, fideliza.perez-manon@hmhn.org

Memorial Sloan Kettering Cancer CenterRECRUITING

New York, New York
Laura Guttentag, 877-649-5622, guttenl@mskcc.org

Mt. Sinai School of MedicineRECRUITING

New York, New York
Anna Blangiardo, 1-800-637-4624, anna.blangiardo@mssm.edu

Atrium Levine Cancer InstituteRECRUITING

Charlotte, North Carolina
Tiffany Drennan, 800-821-1535, Tiffany.Drennan@atriumhealth.org

Tennessee OncologyRECRUITING

Nashville, Tennessee
Faith Dupree, 877-836-6662, fdupree@tnonc.com

ClinicalTrials.gov record


NCT06171685. First posted on 12/15/23

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