Toggle

A drug, QXL138AM, to treat multiple myeloma that has come back (relapsed) or not gotten better with treatment (refractory)

Print

18 and older

Phase 1

8 Locations

NCT06582017

Clinical Trial Goal


To find out:
  • The highest dose of QXL138AM that's safe to give
  • If QXL138AM is safe and works well to treat multiple myeloma that has relapsed or is refractory

You may be able to join this trial if you:


  • Are 18 years old or older
  • Have multiple myeloma that has relapsed or is refractory
  • Have been treated with all of the following (your doctor can tell you this):
    • A drug that targets CD38
    • An IMiD
    • A Proteosome inhibitor
  • Agree to have other standard tests done to see if you can be in the clinical trial 

Trial Details


QXL138AM is an interferon alpha 2 (IFNa2) masked immunocytokine (MIC) that is fused to an antibody that targets CD138.

You’ll get:
  • QXL138AM – Given as intravenous (IV) infusions 1 time every 2 weeks

You'll have biopsies to see how well the treatment is working. The clinical trial doctors will check your health for 3.5 years. 

The Food and Drug Administration (FDA) has not yet approved QXL138AM. 

Contacts


David Stover, PhD, 818-926-3428, David.Stover@nammirx.com

Locations

Cedars-Sanai Medical Center - Samuel Oschin Comprehensive CancerNOT_YET_RECRUITING

Los Angeles, California
Kamya Sankar, MD, 248-802-2041, kamya.sankar@cshs.org

Hoag Memorial Hospital PresbyterianNOT_YET_RECRUITING

Newport, California
Benjamin Goldenson, MD, 949-764-4060, Benjamin.Goldenson@Hoag.org

University of Southern CaliforniaNOT_YET_RECRUITING

Los Angeles, California
Anthony El-Khoueiry, MD, 323-865-3962, elkhouei@med.usc.edu

Sarah Cannon Research Institute - Denver DDUNOT_YET_RECRUITING

Denver, Colorado
Jason T Henry, MD, 720-754-2610, Jason.Henry2@SarahCannon.com

Emory University - Winship Cancer InstituteNOT_YET_RECRUITING

Atlanta, Georgia
Fatemeh Ardeshir, MD, 404-778-0202, fatemeh.ardeshir.larijani@emory.edu

New York Cancer & Blood SpecialistsNOT_YET_RECRUITING

New York, New York
Richard Zuniga, MD, 613-675-5075, zunigaresearch@nycancer.com

University of Rochester - Wilmot Cancer InstituteNOT_YET_RECRUITING

Rochester, New York
Brea Lipe, MD, 585-276-6302, brea_lipe@urmc.rochester.edu

START San AntonioRECRUITING

San Antonio, Texas
Drew Drasco, MD, 210-593-5258, drasco@startsa.com

ClinicalTrials.gov record


NCT06582017. First posted on 9/3/24

Call center employee on the phone offering help to a caller

Questions? Contact our Clinical Trials Navigator

1-888-814-8610
contact@ctsearchsupport.org