Clinical Trial Goal
To find out if AVTX-803 is safe and works well to treat LAD II compared to no treatment
You may be able to join this trial if you:
Your child:
- Is 6 months old or older
- Has LAD II
- Has had infections that haven't gotten better with treatment
- You agree to have other standard tests done to see if your child can be in the clinical trial
Trial Details
AVTX-803 is a plant-made sugar.
In this trial, your child will be randomized to 1 of 2 groups. Once your child is randomized, you, your child and the clinical trial doctors won’t know which group your child is in until after the trial is finished:
In this trial, your child will be randomized to 1 of 2 groups. Once your child is randomized, you, your child and the clinical trial doctors won’t know which group your child is in until after the trial is finished:
- Group 1 – AVTX-803
- Group 2 – Placebo
Randomized means doctors will use a computer to assign your child to either group. A computer assigns your child by chance, like flipping a coin or drawing a name out of a hat. You, your child's doctor or the clinical trial doctor won’t have any control over which group your child will be assigned. This means you won’t be able to choose your child's group.
Your child will get:
- AVTX-803 – Group 1 only – Your child will take this by mouth up to 5 times a day for 8 weeks
- Withdrawal group – Group 2 only – A pill that you take with no medicine in it for 8 weeks
The clinical trial doctors will check your child's health for about 3 months.
The Food and Drug Administration (FDA) has not yet approved AVTX-803.
Locations
Mayo ClinicRECRUITING
Rochester, Minnesota
Eva Morava-Kozicz, MD PhD
Sponsors
lead: AUG Therapeutics
