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A drug, LBS-007, to treat acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML) that has come back (relapsed) or not gotten better with treatment (refractory)

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Phase 1, Phase 2

5 Locations

NCT05756322

Clinical Trial Goal


To find out:
  • The highest dose of LBS-007 that's safe to give
  • If LBS-007 is safe and works well to treat ALL or AML that has relapsed or is refractory

You may be able to join this trial if you:


  • Are 18 years old or older
  • Have ALL or AML that has relapsed or is refractory
  • Do not have acute promyelocytic leukemia
  • Agree to have other standard tests done to see if you can be in the clinical trial 

Trial Details


LBS-007 is a protein kinase inhibitor that targets CDC7.

You’ll get:
  • LBS-007 – The dose you'll get depends on when you start the trial and how safe it has been

You may continue treatment for up to 1 year. You'll have biopsies to see how well the treatment is working. The clinical trial doctors will check your health for 1 year. 

The Food and Drug Administration (FDA) has not yet approved LBS-007.

Contacts


Lin BioScience Clinical Operations, +886975781753, clinicaltrial@linbioscience.com

Locations

Moffitt Cancer CenterNOT_YET_RECRUITING

Tampa, Florida
PI

Robert H. Lurie Comprehensive Cancer Center of Northwestern UniversityNOT_YET_RECRUITING

Chicago, Illinois
PI

The University of Kansas HospitalRECRUITING

Fairway, Kansas
PI

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNOT_YET_RECRUITING

Baltimore, Maryland
PI

UNC Hospitals, The University of North Carolina at Chapel HillRECRUITING

Chapel Hill, North Carolina
PI

ClinicalTrials.gov record


NCT05756322. First posted on 3/6/23

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