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A drug, LBS-007, to treat acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML) that has come back (relapsed) or not gotten better with treatment (refractory)

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18 - 120

Phase 1, Phase 2

5 Locations

NCT05756322

Clinical Trial Goal


To find out:
  • The highest dose of LBS-007 that's safe to give
  • If LBS-007 is safe and works well to treat ALL or AML that has relapsed or is refractory

You may be able to join this trial if you:


  • Are 18 years old or older
  • Have ALL or AML that has relapsed or is refractory
  • Do not have acute promyelocytic leukemia
  • Agree to have other standard tests done to see if you can be in the clinical trial 

Trial Details


LBS-007 is a protein kinase inhibitor that targets CDC7.

You’ll get:
  • LBS-007 – The dose you'll get depends on when you start the trial and how safe it has been

You may continue treatment for up to 1 year. You'll have biopsies to see how well the treatment is working. The clinical trial doctors will check your health for 1 year. 

The Food and Drug Administration (FDA) has not yet approved LBS-007.

Contacts


Lin BioScience Clinical Operations, +886975781753, clinicaltrial@linbioscience.com

Locations

Moffitt Cancer CenterRECRUITING

Tampa, Florida
PI

Robert H. Lurie Comprehensive Cancer Center of Northwestern UniversityNOT_YET_RECRUITING

Chicago, Illinois
PI

The University of Kansas HospitalRECRUITING

Fairway, Kansas
PI

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsRECRUITING

Baltimore, Maryland
PI

UNC Hospitals, The University of North Carolina at Chapel HillRECRUITING

Chapel Hill, North Carolina
PI

ClinicalTrials.gov record


NCT05756322. First posted on 3/6/23

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