That’s according to a new study that included more than 2,500 people, with ages ranging from newborn to 21 years old. Everyone got allogeneic BMT, or cells donated by someone else, for acute leukemia, a form of blood cancer.
BMT can cure leukemia, but it also makes people more vulnerable to germs for a while. So, doctors often give children antibiotics before and after BMT.
A certain group of antibiotics, call carbapenems, was linked to acute graft-versus-host disease (GVHD), a bad side effect that can hurt the skin, liver, stomach and intestines.
Researchers said carbapenems may harm the good bacteria that live in people’s intestines. The good bacteria may help prevent GVHD. Two other groups of antibiotics, cephalosporins and a certain type of penicillin, were also studied. They were not linked to acute GVHD.
Instead of carbapenems, researchers said doctors should consider giving other kinds of antibiotics.