What is sickle cell disease?
BMT sometimes cures sickle cell disease
However, sometimes the healthy cells don’t grow like they should in the bone marrow, and the person isn’t cured.
Who should get a transplant for sickle cell disease?
Researchers studied the medical records of about 1,400 people who got BMT for sickle cell disease. Any of these 3 things raised the likelihood that BMT would work to cure the sickle cell disease:
- Patient was aged 12 or younger during transplant
- Donor was the patient’s brother or sister (people will sickle cell trait can still donate for someone with sickle cell disease)
- Donor was well matched (had similar genes) to the patient
For example, researchers found BMT was most helpful for children who got BMT when they were aged 12 or younger if their disease was severe enough to need a BMT and whose donor was a matched brother or sister. Three years after BMT, 92% (9 out of 10) of these children were alive and had healthy cells.
Ask your doctor
- What is my risk score?
- What are the potential benefits and harms of BMT and other treatments?