While BMT can cure leukemia, it also can have serious side effects. Researchers wanted to learn when BMT is a good choice and how well BMT works for T-PLL.
Researchers studied the medical records of about 270 people who had T-PLL and got BMT during 2008-2018. All the people got allogeneic BMT, meaning cells donated by another person.
Research found BMT can cure T-PLL for years. Research also found people were likely to live longer after BMT if they had any of the following before BMT:
- Got preparative treatments called reduced-intensity conditioning, without getting the medicines anti-thymocyte globulin or alemtuzumab
- Were aged 60 or younger
- Were able to do normal activities and had only minor symptoms before BMT
After being diagnosed with T-PLL, doctors should refer patients to a transplant center as soon as possible.
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