Trial Results
When a clincial trial has reached completion, the results are then summarized into research studies. Use the filter below to explore clinical trial research results.
Reset SearchBlood and marrow transplant can cure sickle cell disease
AgeN/ANumber of Participants950Research GoalImprove SurvivalMost people who live for 2 years or longer after their blood or marrow transplant (BMT) are cured of their disease and can expect to live for many more years. That’s according to new research on BMT and sickle cell disease.Overcoming barriers to health care
AgeN/ANumber of ParticipantsN/AResearch GoalIncrease AccessNMDP helps people get treated for leukemia, sickle cell disease, and other blood disorders.BMT may protect IQ in children with sickle cell disease
Age6-17 years oldNumber of Participants13Research GoalImprove Quality of LifeA small study found that blood or marrow transplant (BMT) may preserve intelligence in children with sickle cell disease.Medicaid does not cover many costs of transplant for people with sickle cell disease
AgeN/ANumber of ParticipantsN/AResearch GoalIncrease AccessSome people with Medicaid insurance face delays or other problems getting blood and marrow transplant (BMT) for sickle cell disease.Blood or marrow transplant can help children with severe sickle cell disease
Age1-49 years oldNumber of Participants996Research GoalImprove SurvivalBlood or marrow transplant (BMT) can help people with severe sickle cell disease, but little was known about the best age for a person to get BMT or which type of donor is best.New risk score predicts person’s chance that transplant will work to treat sickle cell disease
Age1 - 48 years oldNumber of Participants1,425Research GoalImprove SurvivalBlood or marrow transplant (BMT) can cure sickle cell disease for some people. Now, doctors can predict which people will benefit most from BMT.Most children are alive and well after unrelated donor transplant for sickle cell disease
Age6-18Number of Participants21Research GoalImprove SurvivalFor people with sickle cell disease, moderate exercise can improve blood flow in the muscles
Age22 - 44 years oldNumber of Participants33Research GoalImprove Quality of LifeModerate-intensity exercise, like biking, swimming, or fast-paced walking, can help people with sickle cell disease make more blood vessels in their muscles. That’s according to new research.Some children need intensive care after transplant
Age0-21Number of Participants6,995Research GoalImprove SurvivalAlthough blood or marrow transplant (BMT) can cure leukemia, sickle cell disease, and other problems, it can have unwanted effects. The medicines and radiation that help the body prepare for BMT can cause problems. Some of these problems are kidney disease and graft-versus-host disease.Young adults feel more stress after BMT than older adults
Age19-84Number of Participants979Research GoalImprove Quality of LifeAlthough blood or marrow transplant (BMT) can cure blood cancers, sickle cell disease, and other conditions, it also has side effects. A new study of long-term quality of life after BMT shows that young adults, aged 18 to 39, may have lower quality of life than adults aged 40 and older.New treatment may help more people have a safe donor match for blood and marrow transplant
Age15 - 71 years oldNumber of Participants80Research GoalImprove SurvivalMany people don’t have a fully matched family or unrelated donor for a lifesaving blood or marrow transplant (BMT). Now, a new treatment may help more people have a safe mismatched BMT.Lower income children with blood cancers are less likely to survive after blood and marrow transplantation
Age0 - 18 years oldNumber of Participants3,749Research GoalImprove SurvivalChildren who have blood cancers are less likely to survive after transplant if their families are low-income compared to children from higher-income families, a new study found.CAR T-cell therapies treat some types of lymphoma and leukemia
AgeN/ANumber of ParticipantsN/AResearch GoalImprove SurvivalA group of doctors who specialize in blood and marrow transplants, or BMT, now recommend CAR T-cell therapy in some cases.Freezing cells for blood and marrow transplant saves lives
Age19-80 years oldNumber of Participants274Research GoalImprove SurvivalResearch showing that cells can be carefully frozen and stored for blood and marrow transplant (BMT) will save lives during the COVID-19 pandemic and beyond.Changes keep BMT safe and available during pandemic
AgeN/ANumber of ParticipantsN/AResearch GoalNMDP Registry® overcomes COVID-19 challengesGuidelines needed for returning to school after transplant
Number of ParticipantsN/AResearch GoalImprove Quality of LifeBMT may affect hormones and sexual health
Age25-50 yearsNumber of Participants14Research GoalImprove SurvivalImprove Quality of LifeA group of doctors, researchers, and patient advocates published a review of scientific research. They said that BMT sometimes causes problems with hormones and sperm. Also, BMT may cause graft-versus-host disease (GVHD) and secondary cancers that impact the penis, testes, and scrotum.More people get half-matched blood or marrow transplant
AgeLess than 10 to over 70 years oldNumber of Participants93,790Research GoalImprove SurvivalNew medicines have helped people to get a life-saving blood or marrow transplant (BMT) even if they don’t have a fully matched donor.Transplant patients should get vaccinated for COVID-19 early
Number of Participants466Research GoalImprove SurvivalUmbilical cord blood transplants help people of all races
Age1-80 yearsNumber of Participants2,512Research GoalIncrease AccessBlack or African American children may have more side effectsResearchers should ask patients to help plan studies
AgeN/ANumber of ParticipantsN/AResearch GoalImprove Quality of LifeUnlicensed cord blood transplants can help people of color
Age0-81 years oldNumber of Participants2,456Research GoalImprove SurvivalThe largest study of its kind found that unlicensed umbilical cord blood is safe and effective for umbilical cord blood transplant (UCBT).After BMT, children may delay returning to school
AgeN/ANumber of ParticipantsN/AResearch GoalImprove Quality of LifeMost children who have had blood or marrow transplant (BMT) may need to delay returning to school until they have been fully vaccinated for COVID-19.Most patients without fully matched donors now have options
Age0-87Number of Participants9,696Research GoalIncrease AccessImprove SurvivalPeople who need blood or marrow transplant (BMT) have more donor options than before, according to a new study.Young adults may need help returning to work after BMT
Age18-38Number of Participants1,365Research GoalImprove Quality of LifeYoung adults who’ve had allogeneic blood and marrow transplant (BMT) are less likely to be employed than their peers.
Half-matched transplant helps people with aplastic anemia
Number of Participants32Research GoalImprove SurvivalPeople of all races and ethnicities can get successful transplants for severe aplastic anemia (SAA), according to a new study.More tests needed to show when BMT can help older people
AgeN/ANumber of ParticipantsN/AResearch GoalImprove SurvivalBlood and marrow transplant (BMT) is helpful for older people, but only 5-10% of older people who need BMT get this lifesaving treatment.People who get BMT for multiple myeloma have good quality of life
Number of Participants758Research GoalImprove Quality of LifeBlood and marrow transplant (BMT) can control multiple myeloma, a blood cancer. By 1 year after BMT, most people have good quality of life, according to a new study.