Read summaries of completed clinical trials, also called research studies.Reset Search
- AgeN/ANumber of Participants950Research GoalImprove SurvivalMost people who live for 2 years or longer after their blood or marrow transplant (BMT) are cured of their disease and can expect to live for many more years. That’s according to new research on BMT and sickle cell disease.
- Age6-17 years oldNumber of Participants13Research GoalImprove Quality of LifeA small study found that blood or marrow transplant (BMT) may preserve intelligence in children with sickle cell disease.
- Age1-49 years oldNumber of Participants996Research GoalImprove SurvivalBlood or marrow transplant (BMT) can help people with severe sickle cell disease, but little was known about the best age for a person to get BMT or which type of donor is best.
- AgeN/ANumber of ParticipantsN/AResearch GoalIncrease AccessSome people with Medicaid insurance face delays or other problems getting blood and marrow transplant (BMT) for sickle cell disease.
- Age1 - 48 years oldNumber of Participants1,425Research GoalImprove SurvivalBlood or marrow transplant (BMT) can cure sickle cell disease for some people. Now, doctors can predict which people will benefit most from BMT.
- Age22 - 44 years oldNumber of Participants33Research GoalImprove Quality of LifeModerate-intensity exercise, like biking, swimming, or fast-paced walking, can help people with sickle cell disease make more blood vessels in their muscles. That’s according to new research.
- Age19-84Number of Participants979Research GoalImprove Quality of LifeAlthough blood or marrow transplant (BMT) can cure blood cancers, sickle cell disease, and other conditions, it also has side effects. A new study of long-term quality of life after BMT shows that young adults, aged 18 to 39, may have lower quality of life than adults aged 40 and older.
Lower income children with blood cancers are less likely to survive after blood and marrow transplantationAge0 - 18 years oldNumber of Participants3,749Research GoalImprove SurvivalChildren who have blood cancers are less likely to survive after transplant if their families are low-income compared to children from higher-income families, a new study found.
- Age15 - 71 years oldNumber of Participants80Research GoalImprove SurvivalMany people don’t have a fully matched family or unrelated donor for a lifesaving blood or marrow transplant (BMT). Now, a new treatment may help more people have a safe mismatched BMT.
- AgeN/ANumber of ParticipantsN/AResearch GoalImprove SurvivalA group of doctors who specialize in blood and marrow transplants, or BMT, now recommend CAR T-cell therapy in some cases.
- AgeN/ANumber of ParticipantsN/AResearch GoalBe The Match Registry® overcomes COVID-19 challenges
- Age19-80 years oldNumber of Participants274Research GoalImprove SurvivalResearch showing that cells can be carefully frozen and stored for blood and marrow transplant (BMT) will save lives during the COVID-19 pandemic and beyond.
- Age25-50 yearsNumber of Participants14Research GoalImprove Quality of LifeImprove SurvivalA group of doctors, researchers, and patient advocates published a review of scientific research. They said that BMT sometimes causes problems with hormones and sperm. Also, BMT may cause graft-versus-host disease (GVHD) and secondary cancers that impact the penis, testes, and scrotum.
- AgeLess than 10 to over 70 years oldNumber of Participants93,790Research GoalImprove SurvivalNew medicines have helped people to get a life-saving blood or marrow transplant (BMT) even if they don’t have a fully matched donor.
- AgeN/ANumber of ParticipantsN/AResearch GoalImprove Quality of Life
- Age0-81 years oldNumber of Participants2,456Research GoalImprove SurvivalThe largest study of its kind found that unlicensed umbilical cord blood is safe and effective for umbilical cord blood transplant (UCBT).
- AgeN/ANumber of ParticipantsN/AResearch GoalImprove Quality of LifeMost children who have had blood or marrow transplant (BMT) may need to delay returning to school until they have been fully vaccinated for COVID-19.
- Age18-38Number of Participants1,365Research GoalImprove Quality of LifeYoung adults who’ve had allogeneic blood and marrow transplant (BMT) are less likely to be employed than their peers.
- Number of Participants32Research GoalImprove SurvivalPeople of all races and ethnicities can get successful transplants for severe aplastic anemia (SAA), according to a new study.
- AgeN/ANumber of ParticipantsN/AResearch GoalImprove SurvivalBlood and marrow transplant (BMT) is helpful for older people, but only 5-10% of older people who need BMT get this lifesaving treatment.
- Number of Participants758Research GoalImprove Quality of LifeBlood and marrow transplant (BMT) can control multiple myeloma, a blood cancer. By 1 year after BMT, most people have good quality of life, according to a new study.